OZEMPIC and other weight loss jabs have now been linked to ten deaths in the UK.
There have also been 7,228 reports of illness associated with the drugs, citing nausea, vomiting and diarrhoea, according to the medicines watchdog.
And 68 patients were admitted to hospital over their symptoms, the Medicines and Healthcare products Regulatory Agency (MHRA) said.
The reports particularly feature Wegovy and Ozempic, a "miracle" weight loss jab originally designed for managing type 2 diabetes.
They come just a few months after a doctor warned of potential fatalities as a result of the drugs, also known as glucagon-like peptide-1 receptor agonists (GLP-1RAs), after that a young girl was rushed to hospital with life-threatening symptoms.
The reports do not prove that the weight loss jabs are solely responsible for every individual case.
But they do highlight that whoever submitted them to the agency, whether patients or healthcare professionals, had a suspicion that GLP-1RAs may have been a factor.
Speaking to trade magazine Chemist and Druggist, the MHRA reiterated that some of these reports may just be unfortunate coincidences.
However, it did admit that the drugs had unpleasant and widespread side effects associated with it.
Last week, it instructed doctors to "inform patients about the common and serious side effects associated with GLP-1RAs" and "report cases of misuse".
The up-to-date numbers follow last week's estimate of 46 hospitalisations connected with the drugs, as of August 16.
The agency also estimated a 48 per cent increase in reports over the past two months.
Following the findings, it reiterated that drugs like Ozempic and Wegovy should not be used for "unauthorised indications such as aesthetic weight loss".
It also warned of a potential black market for the drugs, advising patients to make sure they are prescribed by a registered professional.
This followed health secretary Wes Streeting's earlier warning that GLP-1RAs are not "cosmetic" treatments - and should only be used in exceptional circumstances.
Mr Streeting, who has also defended the "game changing" potential of the drugs, added: "Weight-loss drugs have enormous potential.
"When taken alongside healthy diet and exercise, they can be game changers in tackling obesity and getting people back to good health.
"But these are not cosmetic drugs that should be taken to help get a body beautiful picture for Instagram.
"These are serious medicines and should only be used responsibly and under medical supervision.
"They're not a quick fix to lose a few pounds and buying them online without appropriate assessment can put people's health at risk.
"Drugs approved for weight management should only be used by those tackling obesity, where diet and exercise has been tried first, and where patients are eligible."
Last month, Mr Streeting defended plans to roll out weight loss jabs among unemployed people to kickstart a major back-to-work drive.